A silicone host for Lumogen dyes

Altering the encapsulant colour in photovoltaic (PV) modules is a straightforward way of achieving greater colour range whilst minimising additional cost in PV systems. Lumogen fluorescent, organic dyes offer a way of adding colour to the encapsulant with minimal change in efficiency. The silicone encapsulant material Sylgard 184 is tested as a host material for Lumogen dyes. A method of dissolving various Lumogen dyes in Sylgard is investigated, and limits of solubility are explored. Methods of preparing samples suitable for optical measurements are found. Optical density is measured for a range of dye concentrations. The results indicate that Lumogen dyes can be dissolved successfully within Sylgard 184, giving good optical properties for lower dye concentrations. Initial photoluminescent quantum yield measurements confirm that Lumogen dyes can function effectively within a Sylgard host. This is promising for use of this material combination in the creation of coloured, fluorescent PV encapsulant layers

The search for building-integrated PV materials with good aesthetic potential: a survey

Building-integrated photovoltaics (PV) is currently dominated by blue and black rectilinear forms. Greater variety of colour and form could lead to much better uptake of PV in the built environment, also increasing the potential for PV to be used as an artistic material. Listing the available PV technologies by colour gives a clearer picture of the current situation. An assessment of photostability, efficiency and price, for each material, indicates the materials that have the potential to fill the gaps in the colour spectrum. Use of combinations of materials that can be fabricated in different ways from the current, standardised, PV modules will further increase the possibilities for use in building integration, Extending the lifetimes of organic PV, dye-sensitised PV or luminescent solar concentrators will increase the possibilities for development of new PV products

Access to healthcare for people seeking and refused asylum in Great Britain: a review of evidence

This research report is a review of evidence looking at the barriers people seeking or refused asylum face in trying to access healthcare services in the UK, and what may help them to do so more easily. This report, and the partner report on lived experiences (https://www.equalityhumanrights.com/en/publication-download/lived-experiences-access-healthcare-people-seeking-and-refused-asylum), will be of interest to people who play an important role in delivering healthcare and related support services to people seeking or refused asylum. We have also made recommendations for what changes are needed (https://www.equalityhumanrights.com/en/publication-download/making-sure-people-seeking-and-refused-asylum-can-access-healthcare-what-needs) to make sure that people seeking and refused asylum have full enjoyment of their right to health. This review was carried out by Imperial College London, with primary data provided by Doctors of the World UK

The micro-foundations of party competition and issue ownership: the reciprocal effects of citizens’ issue salience and party attachments

While previous research on the reciprocal effects of citizens’ issue attitudes and their party support emphasize citizens’ issue positions, political competition revolves equally around issue salience, i.e., debates over which issue areas political parties should prioritize. Using multi-wave panel survey da¬ta from Germany and Great Britain, we analyze the reciprocal effects of citizens’ issue salience and their party support, and we conclude that citizens’ issue priorities both influence and are influenced by their party attachments, and, moreover, that these effects are linked to parties’ long-term associa¬tive issue ownership. This effect is strongest among supporters of a small issue-orientated niche par¬ty, the German Greens

The peritoneal tumour microenvironment of high-grade serous ovarian cancer

High-grade serous ovarian cancer (HGSC) disseminates early and extensively throughout the peritoneal space, causing multiple lesions that are a major clinical problem. The aim of this study was to investigate the cellular composition of peritoneal tumour deposits in patient biopsies and their evolution in mouse models using immunohistochemistry, intravital microscopy, confocal microscopy, and 3D modelling. Tumour deposits from the omentum of HGSC patients contained a prominent leukocyte infiltrate of CD3(+) T cells and CD68(+) macrophages, with occasional neutrophils. Alpha-smooth muscle actin(+) (α-SMA(+) ) pericytes and/or fibroblasts surrounded these well-vascularized tumour deposits. Using the murine bowel mesentery as an accessible mouse peritoneal tissue that could be easily imaged, and two different transplantable models, we found multiple microscopic tumour deposits after i.p. injection of malignant cells. Attachment to the peritoneal surface was rapid (6-48 h) with an extensive CD45(+) leukocyte infiltrate visible by 48 h. This infiltrate persisted until end point and in the syngeneic murine ID8 model, it primarily consisted of CD3(+) T lymphocytes and CD68(+) macrophages with α-SMA(+) cells also involved from the earliest stages. A majority of tumour deposits developed above existing mesenteric blood vessels, but in avascular spaces new blood vessels tracked towards the tumour deposits by 2-3 weeks in the IGROV-1 xenografts and 6 weeks in the ID8 syngeneic model; a vigorous convoluted blood supply was established by end point. Inhibition of tumour cell cytokine production by stable expression of shRNA to CXCR4 in IGROV-1 cells did not influence the attachment of cells to the mesentery but delayed neovascularization and reduced tumour deposit size. We conclude that the multiple peritoneal tumour deposits found in HGSC patients can be modelled in the mouse. The techniques described here may be useful for assessing treatments that target the disseminated stage of this disease

A Handel relative in Britain?

This essay offers a scholarly meditation on a biographical oddity first reported in my doctoral thesis 'Early reception of Handel's oratorios, IJ3Z—IJ84: narrative—studies-documents' (Ann Arbor: UMI, 2004). It also forms a case study of applying surgical focus on a minimal documentary surface. The result IS organic scholarship of open ends, wide implications and joyful inquisitiveness; qualities presently undervalued in academia yet indispensable for genuine humanistic research. I am thankful to Ellen T. Harris for her encouragement and support, and to Karol Berger and Thomas S. Grey for easing my transition to postdoctoral life

Special Libraries, June 1919

Volume 10, Issue 5https://scholarworks.sjsu.edu/sla_sl_1919/1004/thumbnail.jp